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KMID : 0438520080150020183
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Journal of the Korean Society of Neonatology
2008 Volume.15 No. 2 p.183 ~ p.189
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A Congenital Giant hepatic hemangioendothelioma Treated with Interferon-a and Complete Tumor Resection
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Cho Min-A
Park Jun-Eun
Kim Young-Bae
Yu Jae-Eun
Park Moon-Sung
Hong Jeong
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Abstract
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Infantile hepatic hemangioendotheliomas (IHHEs) are benign vascular tumors, but can be associated with the life-threatening complications, such as congestive heart failure, disseminated intravascular coagulation, and massive bleeding. Various therapeutic options have been developed and the treatment response depends on the patient’s clinical status and the nature of the lesion. In the case of a symptomatic IHHE, a non-invasive and precise diagnosis should be performed promptly before the therapeutic method is chosen. Additionally, it should be kept in mind that the residual lesions have malignant potential. We report a case of a congenital giant IHHE that was successfully reduced in size by interferon-α and completely removed by surgical tumor resection with a hepatic lobectomy.
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KEYWORD
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Infantile hepatic hemangioendothelioma, interferon-a
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